Analytical Sciences


Hot Articles

The following 'Hot Articles' have been selected as really HOT by the editorial board members.

Select Volume: 22 / 23 / 24 / 25 / 26 / 27 / 28 / 29 / 30 / 31 / 32 / 33 /

Volume 32, Number 12 (2016)

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A Membrane-integrated Microfluidic Device to Study Permeation of Nanoparticles through Straight Micropores toward Rational Design of Nanomedicines
Naoki SASAKI, Mariko TATANOU, Tomoko SUZUKI, Yasutaka ANRAKU, Akihiro KISHIMURA, Kazunori KATAOKA, and Kae SATO
Keywords: EPR effect, targeting, nanoDDS, nanomedicine, tumor, microchannel
Analytical Sciences, 2016, 32(12), 1307.
DOI: 10.2116/analsci.32.1307, JOI: JST.JSTAGE/analsci/32.1307

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A Simple Method for Ion Channel Recordings Using Fine Gold Electrode
Daichi OKUNO, Minako HIRANO, Hiroaki YOKOTA, Yukiko ONISHI, Junya ICHINOSE, and Toru IDE
Keywords: Ion channel, artificial bilayer, single-channel recording
Analytical Sciences, 2016, 32(12), 1353.
DOI: 10.2116/analsci.32.1353, JOI: JST.JSTAGE/analsci/32.1353

Volume 32, Number 11 (2016)

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Finite Element Analysis on Nanomechanical Sensing of Cellular Forces
Gaku IMAMURA, Kota SHIBA, and Genki YOSHIKAWA
Keywords: Cell motility, mechanobiology, nanomechanical sensors, cantilever-type sensors, membrane-type surface stress sensors (MSS), finite element analysis (FEA)
Analytical Sciences, 2016, 32(11), 1189.
DOI: 10.2116/analsci.32.1189, JOI: JST.JSTAGE/analsci/32.1189

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Design of Tetra-arm PEG-crosslinked Thermoresponsive Hydrogel for 3D Cell Culture
Aya Mizutani AKIMOTO, Erika HASUIKE, Hiroto TADA, Kenichi NAGASE, Teruo OKANO, Hideko KANAZAWA, and Ryo YOSHIDA
Keywords: Poly(N-isopropylacrylamide), hydrogel, thermoresponsive gel, 3D cell culture
Analytical Sciences, 2016, 32(11), 1203.
DOI: 10.2116/analsci.32.1203, JOI: JST.JSTAGE/analsci/32.1203

Volume 32, Number 10 (2016)

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One-pot Synthesis of Quencher Labeled Hairpin DNA–CdTe QDs Conjugate for Target DNA and Deoxyribonuclease I Detection
Qingfeng ZHANG, Juanmin LI, Yunyi ZHANG,, Zhenzhen HU, and Cong YU
Keywords: QDs, target DNA, fluorescence, deoxyribonuclease I, FRET
Analytical Sciences, 2016, 32(10), 1035.
DOI: 10.2116/analsci.32.1035, JOI: JST.JSTAGE/analsci/32.1035

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Highly Sensitive Fluorescence Detection of Hg2+ Based on a Water-soluble Conjugated Polymer with Carboxylate Groups
Hongyu MI, Mingming GUAN, Hongyan SHAN, Qiang FEI, Yanfu HUAN, Zhiquan ZHANG, and Guodong FENG
Keywords: Water-soluble conjugated polymer, Hg2+, fluorescence sensor, environmental water samples
Analytical Sciences, 2016, 32(10), 1039.
DOI: 10.2116/analsci.32.1039, JOI: JST.JSTAGE/analsci/32.1039

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Direct Imaging of Carboxymethyl Cellulose-mediated Aggregation of Lactic Acid Bacteria Using Dark-field Microscopy
Hidenobu NAKAO, Katsuichi SAITO, Satoru TOMITA, Yukio MAGARIYAMA, Yoshihisa KAIZUKA, and Yoshihiko TAKEDA
Keywords: Aggregation, lactic acid bacteria, dark-field microscopy, polysaccharide
Analytical Sciences, 2016, 32(10), 1047.
DOI: 10.2116/analsci.32.1047, JOI: JST.JSTAGE/analsci/32.1047

Volume 32, Number 9 (2016)

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Fluorescence Resonance Energy Transfer-based Biosensor Composed of Nitrogen-doped Carbon Dots and Gold Nanoparticles for the Highly Sensitive Detection of Organophosphorus Pesticides
Nian Chun GONG, Yan Le LI, Xi JIANG, Xiao Fang ZHENG, Ya Ya WANG, and Shuang Yan HUAN
Keywords: Biosensor, nitrogen-doped carbon dots, fluorescence resonance energy transfer, organophosphorus pesticides
Analytical Sciences, 2016, 32(9), 951.
DOI: 10.2116/analsci.32.951, JOI: JST.JSTAGE/analsci/32.951

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Arsenic Speciation and Cadmium Determination in Tobacco Leaves, Ash and Smoke
Takahiro IWAI, Koichi CHIBA, and Tomohiro NARUKAWA
Keywords: Arsenic species, cadmium determination, tobacco leaves, tobacco ash, smoke, monitoring of trace elements
Analytical Sciences, 2016, 32(9), 957.
DOI: 10.2116/analsci.32.957, JOI: JST.JSTAGE/analsci/32.957

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Glucosylation Mediated Rolling Circle Amplification Combined with a qPCR Assay for the Detection of 5-Hydroxymethylcytosine
Di LIU, Chao ZHAO, and Hailin WANG
Keywords: 5-Hydroxymethylcytosine, glucosylation, rolling circle amplification, qPCR
Analytical Sciences, 2016, 32(9), 963.
DOI: 10.2116/analsci.32.963, JOI: JST.JSTAGE/analsci/32.963

Volume 32, Number 8 (2016)

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3,3′,5,5′-Tetramethylbenzidine Oxidation on Paper Devices for Horseradish Peroxidase-based Assays
Lori Shayne Alamo BUSA, Takeshi KOMATSU, Saeed MOHAMMADI, Masatoshi MAEKI, Akihiko ISHIDA, Hirofumi TANI, and Manabu TOKESHI
Keywords: TMB oxidation, horseradish peroxidase, paper-based analytical devices, photolithography, wax-printing
Analytical Sciences, 2016, 32(8), 815.
DOI: 10.2116/analsci.32.815, JOI: JST.JSTAGE/analsci/32.815

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New Electrochemical Evaluation of the Antioxidant Capacity of Beverages with Polyoxometalates as Redox Probes
Tadaharu UEDA, Takashi OKUMURA, Yukino TANAKA, Saki AKASE, Tomoko SHIMAMURA, and Hiroyuki UKEDA
Keywords: Antioxidant, activity, capacity, potentiometry, polyoxometalate
Analytical Sciences, 2016, 32(8), 825.
DOI: 10.2116/analsci.32.825, JOI: JST.JSTAGE/analsci/32.825

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Stepwise Preparation of Spherical Gold Nanoparticles Passivated with Cationic Amphiphiles
Yuki INOUE, Yo TSUTAMOTO, Daiki MUKO, Kazuaki NANAMURA, Tsuyoshi SAWADA, and Yasuro NIIDOME
Keywords: Gold nanoparticle, hexadecyltrimethylammonium bromide, seed-mediated crystal growth
Analytical Sciences, 2016, 32(8), 875.
DOI: 10.2116/analsci.32.875, JOI: JST.JSTAGE/analsci/32.875

Volume 32, Number 7 (2016)

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A Novel Copper(II) Sensor Based on a Unique Water-soluble Porphyrin
Qiang FEI, Hongyan SHAN, Yanfu HUAN, Zhiquan ZHANG, Hongyu MI, Hui XU, Guanghua LI, Fei CHEN, and Guodong FENG
Keywords: Water-soluble porphyrin, absorption spectrum, copper, sensor
Analytical Sciences, 2016, 32(7), 745.
DOI: 10.2116/analsci.32.745, JOI: JST.JSTAGE/analsci/32.745

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Tracing the Geographical Origin of Onions by Strontium Isotope Ratio and Strontium Content
Hisaaki HIRAOKA, Sakie MORITA, Atsunobu IZAWA, Keisuke AOYAMA, Ki-Cheol SHIN, and Takanori NAKANO
Keywords: Agricultural products, geographical origin, isotope ratio, label information, onion, strontium
Analytical Sciences, 2016, 32(7), 781.
DOI: 10.2116/analsci.32.781, JOI: JST.JSTAGE/analsci/32.781

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Shear-Driven Flow Ice Chromatography as a Possible Tool Probing Ice/Water Interface
Masaya SHIMIZU, Makoto HARADA, Akihide HIBARA, and Tetsuo OKADA
Keywords: Shear flow, ice chromatography, electrostatic interaction at ice interface, interface between ice and aqueous solution
Analytical Sciences, 2016, 32(7), 805.
DOI: 10.2116/analsci.32.805, JOI: JST.JSTAGE/analsci/32.805

Volume 32, Number 6 (2016)

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Detection of Methylated DNA on a Power-Free Microfluidic Chip with Laminar Flow-Assisted Dendritic Amplification
Kazuki HASEGAWA, Mutsuyoshi MATSUMOTO, Kazuo HOSOKAWA, and Mizuo MAEDA
Keywords: DNA methylation, detection, immunoassay, power-free microfluidic chip, LFDA
Analytical Sciences, 2016, 32(6), 603.
DOI: 10.2116/analsci.32.603, JOI: JST.JSTAGE/analsci/32.603

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β-Cyclodextrin as a Metal-anionic Porphyrin Complexation Accelerator in Aqueous Media
Takao OHTOMO, Aya YOKOYAMA, Mitsuyuki KONNO, Osamu OHNO, Shukuro IGARASHI, and Yoshitaka TAKAGAI
Keywords: β-Cyclodextrin, metal-anionic porphyrin complexation accelerator, TPPS4
Analytical Sciences, 2016, 32(6), 623.
DOI: 10.2116/analsci.32.623, JOI: JST.JSTAGE/analsci/32.623

Volume 32, Number 5 (2016)

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BODIPY-labeled Fluorescent Aptamer Sensors for Turn-on Sensing of Interferon-gamma and Adenine Compounds on Cells
Akira TSUCHIYA, Siti N. HASHIM, Shoko ISE, Takafumi FURUHATA, Kiyohiko KAWAI, Rie WAKABAYASHI, Masahiro GOTO, Noriho KAMIYA, and Shinsuke SANDO
Keywords: Aptamer, fluorescent sensor, IFN-γ, ATP
Analytical Sciences, 2016, 32(5), 543.
DOI: 10.2116/analsci.32.543, JOI: JST.JSTAGE/analsci/32.543

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Direct Imaging Mass Spectrometry of Plant Leaves Using Surface-assisted Laser Desorption/Ionization with Sputter-deposited Platinum Film
Tomoyuki OZAWA, Issey OSAKA, Satoshi HAMADA, Tatsuya MURAKAMI, Akio MIYAZATO, Hideya KAWASAKI, and Ryuichi ARAKAWA
Keywords: Pt film, imaging mass spectrometry (IMS), surface-assisted laser desorption ionization (SALDI), leaf, agricultural chemicals
Analytical Sciences, 2016, 32(5), 587.
DOI: 10.2116/analsci.32.587, JOI: JST.JSTAGE/analsci/32.587

Volume 32, Number 4 (2016)

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Ag Nanoparticles-enhanced Fluorescence of Terbium-Deferasirox Complexes for the Highly Sensitive Determination of Deferasirox
Jafar ABOLHASANI, Roza NADERALI, and Javad HASSANZADEH
Keywords: Terbium-sensitized fluorescence, deferasirox, Ag nanoparticles, urine
Analytical Sciences, 2016, 32(4), 381.
DOI: 10.2116/analsci.32.381, JOI: JST.JSTAGE/analsci/32.381

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Near-infrared Laser-induced Temperature Elevation in Optically-trapped Aqueous Droplets in Air
Shoji ISHIZAKA, Jiang MA, Terufumi FUJIWARA, Kunihiro YAMAUCHI, and Noboru KITAMURA
Keywords: Laser trapping, Raman spectroscopy, aerosol
Analytical Sciences, 2016, 32(4), 425.
DOI: 10.2116/analsci.32.425, JOI: JST.JSTAGE/analsci/32.425

Volume 32, Number 3 (2016)

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Backward-scattering-based Localized Surface Plasmon Resonance Sensors with Gold Nanospheres and Nanoshells
Tokuhisa KAWAWAKI, Naoaki SHINJO, and Tetsu TATSUMA
Keywords: Localized surface plasmon resonance (LSPR), LSPR sensor, refractive index, light scattering, gold nanoshell
Analytical Sciences, 2016, 32(3), 271.
DOI: 10.2116/analsci.32.271, JOI: JST.JSTAGE/analsci/32.271

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A Rapid and Automated Device for Purifying Nucleic Acids
Masayuki UEHARA, Masato HANAMURA, Kiyohito YAMADA, Akemi YAMAGUCHI, Toshiro MURAYAMA, Yuji SAITO, Kotaro IDEGAMI, and Takayuki HONDA
Keywords: Nucleic acid, extraction, polymerase chain reaction, cartridge, magnetic beads
Analytical Sciences, 2016, 32(3), 371.
DOI: 10.2116/analsci.32.371, JOI: JST.JSTAGE/analsci/32.371

Volume 32, Number 2 (2016)

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Quantitative Live Single-cell Mass Spectrometry with Spatial Evaluation by Three-Dimensional Holographic and Tomographic Laser Microscopy
Ahmed ALI, Yasmine ABOULEILA, Sara AMER, Rie FURUSHIMA, Samy EMARA, Sebastien EQUIS, Yann COTTE, and Tsutomu MASUJIMA
Keywords: Quantitative live single-cell mass spectrometry, three-dimensional imaging, holographic and tomographic microscopy, quantitative single-cell analysis, HepG2 cell
Analytical Sciences, 2016, 32(2), 125.
DOI: 10.2116/analsci.32.125, JOI: JST.JSTAGE/analsci/32.125

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Analysis of Ion Transport through a Single Channel of Gramicidin A in Bilayer Lipid Membranes
Shintaro KUBOTA, Osamu SHIRAI, Yuki KITAZUMI, and Kenji KANO
Keywords: Gramicidin A, bilayer lipid membrane, ion transport, channel, permselectivity, antiport, voltammetry
Analytical Sciences, 2016, 32(2), 189.
DOI: 10.2116/analsci.32.189, JOI: JST.JSTAGE/analsci/32.189

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Forensic Identification of Automobile Window Glass Manufacturers in Japan Based on the Refractive Index, X-ray Fluorescence, and X-ray Absorption Fine Structure
Atsushi FUNATSUKI, Masaki TAKAOKA, Kenji SHIOTA, Daisuke KOKUBU, and Yasuhiro SUZUKI
Keywords: Hit and run accident, source determination, automobile window glass, refractive index, x-ray fluorescence, x-ray absorption fine structure, FEFF simulation
Analytical Sciences, 2016, 32(2), 207.
DOI: 10.2116/analsci.32.207, JOI: JST.JSTAGE/analsci/32.207

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Diagnosis of Periodontal Disease from Saliva Samples Using Fourier Transform Infrared Microscopy Coupled with Partial Least Squares Discriminant Analysis
Satoshi FUJII, Shinobu SATO, Keisuke FUKUDA, Toshinori OKINAGA, Wataru ARIYOSHI, Michihiko USUI, Keisuke NAKASHIMA, Tatsuji NISHIHARA, and Shigeori TAKENAKA
Keywords: Periodontal disease, Fourier transform infrared (FT-IR) microscopy, partial least squares (PLS) discriminant analysis, leave-one-out cross-validation (LOOCV)
Analytical Sciences, 2016, 32(2), 225.
DOI: 10.2116/analsci.32.225, JOI: JST.JSTAGE/analsci/32.225

Volume 32, Number 1 (2016)

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Microfluidic Approaches for Protein Crystal Structure Analysis
Masatoshi MAEKI, Hiroshi YAMAGUCHI, Manabu TOKESHI, and Masaya MIYAZAKI
Keywords: Microfluidic device, protein crystallization, protein crystallography, in-situ X-ray analysis
Analytical Sciences, 2016, 32(1), 3.
DOI: 10.2116/analsci.32.3, JOI: JST.JSTAGE/analsci/32.3

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A Bacterial Continuous Culture System Based on a Microfluidic Droplet Open Reactor
Manami ITO, Haruka SUGIURA, Shotaro AYUKAWA, Daisuke KIGA, and Masahiro TAKINOUE
Keywords: Continuous culture, cell density control, nonequilibrium open system, synthetic biology, genetic engineering, droplet microfluidics, water-in-oil microdroplet, emulsion, nonlinear dynamics, metabolic engineering
Analytical Sciences, 2016, 32(1), 61.
DOI: 10.2116/analsci.32.61, JOI: JST.JSTAGE/analsci/32.61