Analytical Sciences


Hot Articles

The following 'Hot Articles' have been selected as really HOT by the editorial board members.

Select Volume: 22 / 23 / 24 / 25 / 26 / 27 / 28 / 29 / 30 / 31 / 32 / 33 / 34 /

Volume 31, Number 12 (2015)

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Fluorescence Probing Live Single-cell Mass Spectrometry for Direct Analysis of Organelle Metabolism
Tsuyoshi ESAKI and Tsutomu MASUJIMA
Keywords: Single-cell analysis, live single-cell mass spectrometry, fluorescence imaging, mitochondria, organelle
Analytical Sciences, 2015, 31(12), 1211.
DOI: 10.2116/analsci.31.1211, JOI: JST.JSTAGE/analsci/31.1211

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Direct Lipido-Metabolomics of Single Floating Cells for Analysis of Circulating Tumor Cells by Live Single-cell Mass Spectrometry
Eiso HIYAMA, Ahmed ALI, Sara AMER, Takanori HARADA, Kazumi SHIMAMOTO, Rie FURUSHIMA, Yasmine ABOULEILA, Samy EMARA, and Tsutomu MASUJIMA
Keywords: Live single-cell mass spectrometry, circulating tumor cell, neuroblastoma, floating cells, lipido-metabolomics, one-drop blood analysis
Analytical Sciences, 2015, 31(12), 1215.
DOI: 10.2116/analsci.31.1215, JOI: JST.JSTAGE/analsci/31.1215

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Low-cost Methods for Making 3D Fluidic Polymer and Glass Chips Using Metal Templates
Tomohisa YAMASHITA, Kazuyuki YASUKAWA, Tomoko KEMMEI, Yuuko HORII, Eriko NAKAYAMA, Tatsuya MURAMOTO, and Hiroshi TAKADA
Keywords: Fluidic chip, 3D chip, PDMS, glass, epoxy, template
Analytical Sciences, 2015, 31(12), 1261.
DOI: 10.2116/analsci.31.1261, JOI: JST.JSTAGE/analsci/31.1261

Volume 31, Number 11 (2015)

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Development of a Fully-automated On-line Oxidation Column-switching HPLC System for the Determination of Endogenous Melatonin in Human Clinical Samples
Tsubasa OYAMA, Rie NAGAI, Mayumi FUJIMOTO, Ryoko KONISHI, Masashi MITA, Keiko UEZONO, Kiyoshi ZAITSU, and Kenji HAMASE
Keywords: Melatonin, column-switching, fluorescence, on-line oxidation, HPLC
Analytical Sciences, 2015, 31(11), 1129.
DOI: 10.2116/analsci.31.1129, JOI: JST.JSTAGE/analsci/31.1129

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A Portable Liquid Chromatograph with a Battery-operated Compact Electroosmotic Pump and a Microfluidic Chip Device with a Reversed Phase Packed Column
Akihiko ISHIDA, Mitsutaka FUJII, Takehiro FUJIMOTO, Shunsuke SASAKI, Ichiro YANAGISAWA, Hirofumi TANI, and Manabu TOKESHI
Keywords: Electroosmotic pump, liquid chromatography, microfluidic chip, packed column
Analytical Sciences, 2015, 31(11), 1163.
DOI: 10.2116/analsci.31.1163, JOI: JST.JSTAGE/analsci/31.1163

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Simple and Rapid Immobilization of Coating Polymers on Poly(dimethyl siloxane)-glass Hybrid Microchips by a Vacuum-drying Method
Fumihiko KITAGAWA, Syo NAKAGAWARA, Isoshi NUKATSUKA, Yusuke HORI, Kenji SUEYOSHI, and Koji OTSUKA
Keywords: Microchip electrophoresis, vacuum-drying method, polymer coating, electroosmotic flow, bioanalysis
Analytical Sciences, 2015, 31(11), 1171.
DOI: 10.2116/analsci.31.1171, JOI: JST.JSTAGE/analsci/31.1171

Volume 31, Number 10 (2015)

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Cation-driven Optical Properties of Artificial Luciferases
Sung Bae KIM, Simon MILLER, Nobuhiro SUZUKI, Toshiya SENDA, Ryo NISHIHARA, and Koji SUZUKI
Keywords: Bioluminescence, metal cation, artificial Luciferase, supersecondary structure code
Analytical Sciences, 2015, 31(10), 955.
DOI: 10.2116/analsci.31.955, JOI: JST.JSTAGE/analsci/31.955

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Changes in Interfacial Tension of a Lipid Membrane Formed at the Water/Chloroform Interface upon DNA Complex Formation
Masashi OHNO, Taro TOYOTA, Tomonori NOMOTO, and Masanori FUJINAMI
Keywords: Quasi-elastic laser scattering (QELS) method, DNA complexation, lipid membrane, water/chloroform interface
Analytical Sciences, 2015, 31(10), 979.
DOI: 10.2116/analsci.31.979, JOI: JST.JSTAGE/analsci/31.979

Volume 31, Number 9 (2015)

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On-chip FRET Graphene Oxide Aptasensor: Quantitative Evaluation of Enhanced Sensitivity by Aptamer with a Double-stranded DNA Spacer
Yuko UENO, Kazuaki FURUKAWA, Andrew TIN, and Hiroki HIBINO
Keywords: Graphene, graphene oxide, aptamer, DNA, protein, biosensor, aptasensor, fluorescence, fluorescence resonance energy transfer, microchannel
Analytical Sciences, 2015, 31(9), 875.
DOI: 10.2116/analsci.31.875, JOI: JST.JSTAGE/analsci/31.875

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Temperature-responsive Solid-phase Extraction Column for Biological Sample Pretreatment
Michiko AKIMARU, Kohei OKUBO, Yuki HIRUTA, and Hideko KANAZAWA
Keywords: Solid phase extraction, poly(N-isopropylacrylamide), temperature-responsive packing materials, protein, human serum albumin, pretreatment, phenytoin, theophylline
Analytical Sciences, 2015, 31(9), 881.
DOI: 10.2116/analsci.31.881, JOI: JST.JSTAGE/analsci/31.881

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Repeatability Assessment by ISO 11843-7 in Quantitative HPLC for Herbal Medicines
Liangmian CHEN, Akira KOTANI, Hideki HAKAMATA, Risa TSUTSUMI, Yuzuru HAYASHI, Zhimin WANG, and Fumiyo KUSU
Keywords: HPLC, ISO 11843-7, repeatability, system suitability testing, validation
Analytical Sciences, 2015, 31(9), 903.
DOI: 10.2116/analsci.31.903, JOI: JST.JSTAGE/analsci/31.903

Volume 31, Number 8 (2015)

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Kinetic Study of the Intermolecular Interaction between 2-Phenoxypropionic Acid and β-Bromo-cyclodextrin Affixed on the Stationary Phase by Liquid Chromatography
Kanji MIYABE and Satoshi KAMIYA
Keywords: Intermolecular interaction, moment analysis, reaction kinetics, association rate constant, dissociation rate constant, Langmuir-type rate equation, equilibrium constant, chiral HPLC system
Analytical Sciences, 2015, 31(8), 743.
DOI: 10.2116/analsci.31.743, JOI: JST.JSTAGE/analsci/31.743

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Development of Desolvation System for Single-cell Analysis Using Droplet Injection Inductively Coupled Plasma Atomic Emission Spectroscopy
Yukiko ISHIHARA, Mari AIDA,Akito NOMURA, Hidekazu MIYAHARA, Akiko HOKURA, and Akitoshi OKINO
Keywords: ICP-AES, desolvation system, single-cell analysis, micro-droplet injection system
Analytical Sciences, 2015, 31(8), 781.
DOI: 10.2116/analsci.31.781, JOI: JST.JSTAGE/analsci/31.781

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A Novel Sensor for Sensitive and Selective Detection of Iodide Using Turn-on Fluorescence Graphene Quantum Dots/Ag Nanocomposite
Xianghong XU and Yanhui WANG
Keywords: Graphene quantum dots, fluorescence, silver, iodide anion
Analytical Sciences, 2015, 31(8), 787.
DOI: 10.2116/analsci.31.787, JOI: JST.JSTAGE/analsci/31.787

Volume 31, Number 7 (2015)

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Yeast-based Biochemical Oxygen Demand Sensors Using Gold-modified Boron-doped Diamond Electrodes
Tribidasari A. IVANDINI, HARMESA, Endang SAEPUDIN, and Yasuaki EINAGA
Keywords: Gold-modified diamond, BOD sensors, oxygen, Rhodotorula mucilaginosa UICC Y-181, alginate matrix
Analytical Sciences, 2015, 31(7), 643.
DOI: 10.2116/analsci.31.643, JOI: JST.JSTAGE/analsci/31.643

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An Electrochemical Biosensor Based on a Myoglobin-specific Binding Peptide for Early Diagnosis of Acute Myocardial Infarction
Hyeong Yun LEE, Ji Suk CHOI, Padmanaban GURUPRASATH, Byung-Heon LEE, and Yong Woo CHO
Keywords: Electrochemical sensor, myoglobin, myoglobin-specific binding peptide, gold electrode
Analytical Sciences, 2015, 31(7), 699.
DOI: 10.2116/analsci.31.699, JOI: JST.JSTAGE/analsci/31.699

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An Extended-gate Type Organic FET Based Biosensor for Detecting Biogenic Amines in Aqueous Solution
Tsuyoshi MINAMI, Tsubasa SATO, Tsukuru MINAMIKI, and Shizuo TOKITO
Keywords: Organic field-effect transistor, histamine, putrescine, osmium polymer, horseradish peroxidase, diamine oxidase
Analytical Sciences, 2015, 31(7), 721.
DOI: 10.2116/analsci.31.721, JOI: JST.JSTAGE/analsci/31.721

Volume 31, Number 6 (2015)

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Photoluminescent Detection of Nitrite with Carbon Nanodots Prepared by Microwave-assisted Synthesis
Kotaro MORITA, Akane KOBAYASHI, Hirohisa NAGATANI, and Hisanori IMURA
Keywords: Carbon nanodots, photoluminescence, nitrite, p-phenylenediamine
Analytical Sciences, 2015, 31(6), 481.
DOI: 10.2116/analsci.31.481, JOI: JST.JSTAGE/analsci/31.481

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Fluorescence Enhancement of Nanoraspberry Hot-spot Source Composed of Gold Nanoparticles and Aniline Oligomers
Takamasa KINOSHITA, Dung Quang NGUYEN, Tomoaki NISHINO, Hidenobu NAKAO, Hiroshi SHIIGI, and Tsutomu NAGAOKA
Keywords: Gold nanoparticles, fluorescence enhancement, hot-spot
Analytical Sciences, 2015, 31(6), 487.
DOI: 10.2116/analsci.31.487, JOI: JST.JSTAGE/analsci/31.487

Volume 31, Number 5 (2015)

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Temporal Changes of Fractionation Index Caused by Changes in the Large Size of Ablated Particles in Laser Ablation–Inductively Coupled Plasma Mass Spectrometry
Ryo MACHIDA, Takashi NAKAZAWA, and Naoki FURUTA
Keywords: Elemental fractionation, laser ablation, ICP-MS, NIST glass, fractionation index, large ablated particles, SEM, defocus
Analytical Sciences, 2015, 31(5), 345.
DOI: 10.2116/analsci.31.345, JOI: JST.JSTAGE/analsci/31.345

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Double-sided Microfluidic Device for Speciation Analysis of Iron in Water Samples: Towards Greener Analytical Chemistry
Napaporn YOUNGVISES, Porapichcha THANURAK, Thanatcha CHAIDA, Jaroon JUKMUNEE, and Awadh ALSUHAIMI
Keywords: Double-sided, microfluidic lab-on-a-chip, iron speciation, green analytical chemistry, natural water
Analytical Sciences, 2015, 31(5), 365.
DOI: 10.2116/analsci.31.365, JOI: JST.JSTAGE/analsci/31.365

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A Novel Analysis Method for Lactate Dehydrogenase Activity in Serum Samples Based on Fluorescence Capillary Analysis
Qiao-Jing LI, Yong-Sheng LI, and Xiu-Feng GAO
Keywords: Fluorescence capillary analysis, immobilized enzyme, biosensor, pyruvate, lactate, lactate dehydrogenase
Analytical Sciences, 2015, 31(5), 413.
DOI: 10.2116/analsci.31.413, JOI: JST.JSTAGE/analsci/31.413

Volume 31, Number 4 (2015)

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Evaluation of Enzymatic Activities in Living Systems with Small-molecular Fluorescent Substrate Probes
Toru KOMATSU, and Yasuteru URANO
Analytical Sciences, 2015, 31(4), 257.
DOI: 10.2116/analsci.31.257, JOI: JST.JSTAGE/analsci/31.257

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Multimodal Imaging of Living Cells with Multiplex Coherent Anti-stokes Raman Scattering (CARS), Third-order Sum Frequency Generation (TSFG) and Two-photon Excitation Fluorescence (TPEF) Using a Nanosecond White-light Laser Source
Hiroki SEGAWA, Masanari OKUNO, Philippe LEPROUX, Vincent COUDERC, Takeaki OZAWA, and Hideaki KANO
Analytical Sciences, 2015, 31(4), 299.
DOI: 10.2116/analsci.31.299, JOI: JST.JSTAGE/analsci/31.299

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Multi-point Scanning Two-photon Excitation Microscopy by Utilizing a High-peak-power 1042-nm Laser
Kohei OTOMO, Terumasa HIBI, Takashi MURATA, Hirotaka WATANABE, Ryosuke KAWAKAMI, Hiroshi NAKAYAMA, Mitsuyasu HASEBE, and Tomomi NEMOTO
Analytical Sciences, 2015, 31(4), 307.
DOI: 10.2116/analsci.31.307, JOI: JST.JSTAGE/analsci/31.307

Volume 31, Number 3 (2015)

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High-Contrast Fluorescence Imaging Based on the Polarization Dependence of the Fluorescence Enhancement Using an Optical Interference Mirror Slide
Mitsuru YASUDA and Takuo AKIMOTO
Keywords: Enhanced fluorescence, biochip, polarization
Analytical Sciences, 2015, 31(3), 139.
DOI: 10.2116/analsci.31.139, JOI: JST.JSTAGE/analsci/31.139

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Screen Printed Paper-based Diagnostic Devices with Polymeric Inks
Ju-Yen SUN, Chao-Min CHENG, and Ying-Chih LIAO
Keywords: Paper-based diagnostic devices, polymers, screen printing
Analytical Sciences, 2015, 31(3), 145.
DOI: 10.2116/analsci.31.145, JOI: JST.JSTAGE/analsci/31.145

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Self-assembled Nanowire Arrays as Three-dimensional Nanopores for Filtration of DNA Molecules
Sakon RAHONG, Takao YASUI, Takeshi YANAGIDA, Kazuki NAGASHIMA, Masaki KANAI, Gang MENG, Yong HE, Fuwei ZHUGE, Noritada KAJI, Tomoji KAWAI, and Yoshinobu BABA
Keywords: Nanowire, 3D nanopore structure, biomolecular filtration
Analytical Sciences, 2015, 31(3), 153.
DOI: 10.2116/analsci.31.153, JOI: JST.JSTAGE/analsci/31.153

Volume 31, Number 2 (2015)

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Effects of Densities of Brominated Flame Retardants on the Detection Response for HPLC Analysis with a Corona-charged Aerosol Detector
Shigetomo MATSUYAMA, Yukari ORIHARA, Shinichi KINUGASA, and Hajime OHTANI
Keywords: Corona-charged aerosol detector, HPLC, density, concentration, response, brominated flame retardants
Analytical Sciences, 2015, 31(2), 61.
DOI: 10.2116/analsci.31.61, JOI: JST.JSTAGE/analsci/31.61

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Integration of a Reconstituted Cell-free Protein-synthesis System on a Glass Microchip
Yo TANAKA and Yoshihiro SHIMIZU
Keywords: Cell-free protein synthesis system, PURE system, continuous flow, microchip
Analytical Sciences, 2015, 31(2), 67.
DOI: 10.2116/analsci.31.67, JOI: JST.JSTAGE/analsci/31.67

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Silicon Nanowire Biosensor for Highly Sensitive and Multiplexed Detection of Oral Squamous Cell Carcinoma Biomarkers in Saliva
Yulin ZHANG, Rongmei CHEN, Lu XU, Yong NING, Shenggao XIE, and Guo-Jun ZHANG
Keywords: Silicon nanowire, field effect transistor, biosensors, biomarker, detection, saliva
Analytical Sciences, 2015, 31(2), 73.
DOI: 10.2116/analsci.31.73, JOI: JST.JSTAGE/analsci/31.73

Volume 31, Number 1 (2015)

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Evaluation of the Water-treatment Ability of Silica-doped Titanium Dioxide-coated Glass Plates Using a Cationic Coupling Reagent Based on a Flow Analytical System
Tsuyoshi SUGITA, Masanobu MORI, Akinori MASE, Shin-nosuke NOGUCHI, Toru TOKUTOME, Kengo FUJII, Chisato HARA, Kenji KATAYAMA, Shinji IWAMOTO, and Hideyuki ITABASHI
Keywords: Flow analysis, photocatalyst, adsorption, decomposition, plate, coating
Analytical Sciences, 2015, 31(1), 15.
DOI: 10.2116/analsci.31.15, JOI: JST.JSTAGE/analsci/31.15

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Ion Sensing by Charge Transfer Absorption Variations of Benzocrown–Bipyridinium Conjugates with an Alkyl Chain
Tetsuo KUWABARA, Ryota SATAKE, and Haocheng GUO
Keywords: Chemosensor, ion sensing, intramolecular charge transfer absorption, host-guest chemistry, crown ether, bipyridinium
Analytical Sciences, 2015, 31(1), 23.
DOI: 10.2116/analsci.31.23, JOI: JST.JSTAGE/analsci/31.23

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Ultrasensitive Biosensor for Detection of Organophosphorus Pesticides Based on a Macrocycle Complex/Carbon Nanotubes Composite and 1-Methyl-3-octylimidazolium Tetrafluoroborate as Binder Compound
Neuma das Mercês PEREIRA, Fernando Mota de OLIVEIRA, Nara Rúbia PEREIRA, Rodrigo Moreira VERLY, Dênio Emanuel Pires SOUTO, Lauro Tatsuo KUBOTA, Auro Atsushi TANAKA, Flavio Santos DAMOS, and Rita de Cássia Silva LUZ
Keywords: Biosensor, cetylcholinesterase, CoTsPc, CNT, OMIM[BF4], OP pesticides
Analytical Sciences, 2015, 31(1), 29.
DOI: 10.2116/analsci.31.29, JOI: JST.JSTAGE/analsci/31.29