Analytical Sciences

Abstract − Analytical Sciences, 28(9), 901 (2012).

Matrix-assisted Laser Desorption Ionization Mass Spectrometry of Maltohexaose and Acetylsalicylic Acid Using Alkali Metal Cation-substituted Zeolites
Junya SUZUKI and Tatsuya FUJINO
Department of Chemistry, Graduate School of Science and Engineering, Tokyo Metropolitan University, 1-1 Minami-Osawa, Hachioji, Tokyo 192-0397, Japan
Using alkali-metal cation-substituted zeolites and 2,4,6-trihydroxyacetophenone (THAP), which is a typical organic matrix molecule for matrix-assisted laser desorption ionization (MALDI), mass spectrometry has been performed for maltohexaose and acetylsalicylic acid, and the cation-selective ionization of these analytes was achieved. It is found that a complex of cation-substituted zeolite and THAP can be applicable to a compound that is hard to be ionized by a proton adduction in conventional MALDI.