Analytical Sciences

Abstract − Analytical Sciences, 28(9), 833 (2012).

Magnetic-Force Quartz Crystal Microbalance for the Detection of Chemical Interactions
Shinichi IMAI* and Hitoshi WATARAI**
*Department of Chemistry, Graduate School of Science, Osaka University, Toyonaka, Osaka 560-0043, Japan
**Institute for NanoScience Design, Osaka University, Toyonaka, Osaka 560-8531, Japan
The magnetic-force quartz crystal microbalance (QCM) method was attempted for the dynamic evaluation of chemical interactions. Thiol-modified magnetic particles bound to a QCM gold electrode of less than three layers were pulled by a magnetic force, and the dissociation dynamics of the magnetic particles was measured based on the change in the weight as a function of time under different temperatures. From an analysis of the dissociated layers and the activation energy for the dissociation, the chemical interactions between particles were evaluated.