Analytical Sciences

Abstract − Analytical Sciences, 28(7), 705 (2012).

Characterization of MgFe2O4 Nanoparticles as a Novel Electrochemical Sensor: Application for the Voltammetric Determination of Ciprofloxacin
Department of Chemistry, Isfahan University of Technology, Isfahan 84156-83111, Iran
A new sensor containing MgFe2O4 nanoparticles in modified multiwall carbon nanotubes (MgFe2O4-MWCNTs) was prepared, and its electrochemical behavior was investigated. MgFe2O4-MWCNTs were used as a voltammetric sensor for the electrocatalytic determination of ciprofloxacin. The synthesized materials were characterized by different methods such as transmission electron microscopy (TEM), X-ray diffraction (XRD), cyclic voltammetry, and electrochemical impedance spectroscopy. The MgFe2O4-MWCNTs electrode showed an oxidation peak potential at around 250 mV. The immobilized composite films facilitate interfacial electron transfer and electrocatalytic activity on the oxidation of ciprofloxacin. The oxidation peak current was dependent on the ciprofloxacin concentration, which was linear over the range of 0.10 – 1000 μmol L−1 with a detection limit and quantification limit of 0.01 and 0.08 μmol L−1, respectively. The relative standard deviation for the determination of 1.0 μmol L−1 ciprofloxacin was 1.1%. The repeatability of the sensor was investigated by preparing nine similar electrodes. The proposed sensor is a selective and fast tool for the determination of ciprofloxacin in tablet, plasma, and urine samples.