Analytical Sciences

Abstract − Analytical Sciences, 27(9), 921 (2011).

Electrochemical Determination of Dopamine in the Presence of Ascorbic Acid and Uric Acid Using the Synergistic Effect of Gold Nanoflowers and L-Cysteamine Monolayer at the Surface of a Gold Electrode
Yongxin LI,* Qiufang LU,* Aibin SHI,** Yuanli CHEN,* Shengnan WU,* and Lun WANG*
*Anhui Key Laboratory of Chemo-Biosensing, College of Chemistry and Materials Science, Anhui Normal University, Wuhu 241000, P. R. China
**Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA
This paper describes a facile and effective method to synthesize gold nanoflowers (AuNFs) by a controllable electrodeposition method induced by a L-cysteamine (L-Cys) monolayer self-assembled on the surface of a gold electrode. The AuNFs/L-Cys/Au electrodes were characterized by field emission scanning electron microscopy (FE-SEM), cyclic voltammetry, and AC impedance spectroscopy methods. This obtained AuNFs/L-Cys/Au electrode exhibits excellent electrocatalytic activity towards the oxidation of dopamine (DA) due to the synergistic effect of AuNFs and a L-Cys monolayer. Differential pulse voltammetry (DPV) experiment results show that the oxidation peak of DA is separated from the oxidation peaks of ascorbic acid (AA) and uric acid (UA), which can be used to detect DA in the presence of AA and UA, and the results are satisfactory.