Analytical Sciences

Abstract − Analytical Sciences, 21(4), 373 (2005).

Terbium Sensitized Determination of Tosufloxacin Using Electrochemiluminescence Method
Yu LIU, Shilv CHEN, Huichun ZHAO, and Linpei JIN
Department of Chemistry, Beijing Normal University, Beijing 100875, P. R. China
A novel method for determination of trace amounts of tosufloxacin (TFLX) based on electrochemiluminescence (ECL) has been developed. The calibration graphs for TFLX were linear in the range of 5.0 × 10-11 - 3.5 × 10-7 mol/L, with the detection limit of 1.3 × 10-11 mol/L. Key factors affecting the determination of TFLX were investigated. TFLX amounts in capsule and serum samples were successfully detected by this method. A possible mechanism of energy transfer, and thus the explanation of ECL in the Tb3+-TFLX-Na2S2O4 system are discussed.