Analytical Sciences

Abstract − Analytical Sciences, 18(6), 635 (2002).

Electrocatalytic Response of Dopamine at a Metallothioneins Self-Assembled Gold Electrode
Qian WANG, Nanqiang LI,  and Wenqing WANG
Department of Chemistry, Peking University, Beijing 100871, People's Republic of China
The metallothioneins (MT) self-assembled monolayer modified gold electrode (MT/Au) is demonstrated to catalyze the electrochemical response of dopamine (DA) by cyclic voltammetry. A pair of well-defined redox waves was obtained and the calculated standard rate constant (ks) is 6.97 x 10-3 cm s-1 (20°C) at the self-assembled electrode. The electrode reaction is a quasi-reversible process. The oxidation peak of DA can be used to determine the concentration of DA. The peak current and the concentration of DA follow a linear relationship in the range of 2.0 x 10-5 M to 8.0 x 10-4 M. The detection limit is 6.0 x 10-6 M. By ac impedance spectroscopy, the apparent electron transfer rate constant (kapp) of Fe(CN)63-/Fe(CN)64- at the MT/Au electrode was obtained as 2.0 x 10-5 cm s-1. The MT/Au was characterized with grazing angle FT-IR spectroscopy and contact angle goniometry.