Analytical Sciences

Abstract − Analytical Sciences, 17(9), 1095 (2001).

Flow-Injection Electrogenerated Chemiluminescence Determination of Isoniazid Using Luminol
Xingwang ZHENG, Zhihui GUO, and Zhujun ZHANG 
Department of Chemistry, Shaanxi Normal University, Xi'an 710062, P. R. China
Based on a new electrogenerated chemiluminescence (ECL) analytical idea, this paper explains a sensitive and selective flow-injection ECL method using luminol for the determination of isoniazid, based on the sensitizing effect of isoniazid for the weak ECL emission of electrochemically oxidized luminol. Under the optimum experimental conditions, the relative ECL intensity was linear with isoniazid concentration in the range of 4.0 x 10-8 mol/L to 8.0 x 10-6 mol/L and with a detecting limit of 2.8 x 10-8 mol/L.