Analytical Sciences

Abstract − Analytical Sciences, 37(4), 633 (2021).

Electrochemical Detection of Sesamol Dimer and its Application to Measurement of Radicals
Ken-ichi OHNO,* Katsuhiko SATO,** Masayuki KUMANO,*** Kazuhiro WATANABE,** and Tsutomu FUJIMURA**
*Faculty of Pharmaceutical Sciences, Teikyo Heisei University, 4-21-2 Nakano, Nakano, Tokyo 164-8530, Japan
**Faculty of Pharmaceutical Sciences, Tohoku Medical and Pharmaceutical University, 4-1 Komatsushima 4-chome, Aoba, Sendai, Miyagi 981-8558, Japan
***Faculty of Pharmaceutical Sciences, Tohoku University, 6-3 Aoba, Aramaki, Aoba, Sendai, Miyagi 980-8578, Japan
In this paper we propose a novel measurement for NO and ·OH by electrochemical detection using sesamol. Standard samples of the sesamol monomer and dimer were subjected to differential pulse voltammetry, resulting in their peaks being clearly separated and detected. Based on the oxidative dimerization of sesamol, the current simple, sensitive and selective method was successfully applied to preliminary measurements for NO and ·OH, respectively.