Analytical Sciences

Abstract − Analytical Sciences, 36(9), 1045 (2020).

Core-shell Au@Pt Nanoparticles Catalyzed Luminol Chemiluminescence for Sensitive Detection of Thiocyanate
Ze WANG,* Bin DONG,* Xiaoqian CUI,** Qian FAN,*** Yanfu HUAN,* Hongyan SHAN,* Guodong FENG,* and Qiang FEI*
*Department of Analytical Chemistry, College of Chemistry, Jilin University, Jiefang 2519, Changchun 130012, P. R. China
**Department of Emergency and Critical Care, the Second Hospital of Jilin University, Changchun 130041, P. R. China
***Changchun Polytechnic, Changchun 130033, P. R. China
In this study, core-shell Au@Pt nanoparticles (Au@Pt NPs) with peroxidase catalytic activity were synthesized by the seed-mediated method, and were used to catalyze the reaction of luminol–H2O2 to enhance the chemiluminescence (CL) intensity. It was found that thiocyanate (SCN) can effectively inhibit the catalytic activity of Au@Pt NPs. Based on this phenomenon, a method to detect SCN by using the Au@Pt NPs-catalytic luminol–H2O2 CL system was established, which has an ultra-low detection limit and an ultra-wide linear range, as well as the advantages of being simple and having low-cost and convenient operation. The research mechanism indicated that SCN could be adsorbed on the surface of Au@Pt NPs and occupies the active sites of Pt nanostructures, which led to a decrease in the amount of Pt0 and a loss of the excellent catalytic activity of Au@Pt NPs. After optimizing the experimental conditions, this assay for detecting SCN exhibited a good linear range from 5 to 180 nM, and the low detection limit was 2.9 nM. In addition, this approach has been successfully applied to the detection of SCN in tap-water samples, which has practical application value and embodies good development prospects.