Analytical Sciences

Abstract − Analytical Sciences, 35(10), 1097 (2019).

The Effect of Oxidative Debris on the Laser Desorption/Ionization Efficiency of Graphene Oxide Derivatives for Mass Spectrometric Analysis of Small Molecules and Synthetic Polymers
Yu Lim HONG,* Tae Hoon SEO,** Hongje JANG,*** and Young-Kwan KIM*
*Carbon Composite Materials Research Center, Institute of Advanced Composite Materials, Korea Institute of Science and Technology, San 101, Eunha-ri, Bongdong-eup, Wanju-gun, Jeollabuk-do 565-905, Korea
**Nano-Photonics Convergence Technology Group, Korea Institute of Industrial Technology, 6, Cheomdan-gwagiro 208-gil, Buk-gu, Gwangju 61012, Korea
***Department of Chemistry, Kwangwoon University, 20 Gwangwoon-ro, Nowon-gu, Seoul 01897, Korea
The influence of oxidative debris (OD) on laser desorption/ionization time of flight mass spectrometry (LDI-TOF-MS) analysis using graphene oxide (GO) derivatives was systematically investigated. Specifically, the effects on LDI-TOF-MS analysis of small molecules and synthetic polymers were highlighted. The analytical efficiency of GO was significantly enhanced by removing OD from its surface and the working molecular weight range of GO was considerably extended for analysis of synthetic polymers and small molecules.