Analytical Sciences

Abstract − Analytical Sciences, 34(10), 1111 (2018).

A Highly Selective and Sensitive Colorimetric Probe for Cu2+ Determination in Aqueous Media Based on Derivative of Tryptanthrin
Yawei LIANG,* Xinna WANG,* Huanle FANG,** Ningjuan HAN,** Cuiling WANG,* Zhiqiang XIAO,*** Aihua ZHU,*** and Jianli LIU*
*Key Laboratory of Resource Biology and Biotechnology in Western China, Ministry of Education, College of Life Science, Northwest University, Xi’an, 710069, China
**School of Medicine, Xi’an Peihua University, Xi’an, 710125, China
***Shaanxi Key Laboratory of Chinese Medicine and Natural Medicine Research and Development, Xi’an, 710075, China
A new colorimetric probe, based on tryptanthrin derivative (TR-A), has been successfully synthesized. The probe shows good selectivity and sensitivity for Cu2+ over 12 competing metal ions in a 10 mM Tris–HCl buffer solution (pH 5.5). A significant peak at 623nm appears in the UV-Vis absorption of TR-A-Cu2+, and a noteworthy color change is observed with the naked eye from aquamarine blue to light orange. The interaction of TR-A and Cu2+ are proven to form a 1:1 binding stoichiometry; this identifying is expected to be completed within 1 min. The probe with a limit of detection (16 nM, R2 = 0.9934) shows excellent potential to determine Cu2+ in analysis systems.