Analytical Sciences

Abstract − Analytical Sciences, 32(4), 407 (2016).

Determination of Earthy-musty Odorous Compounds in Drinking Water by Vortex Assisted Dispersive Liquid–Liquid Microextraction Combined with Gas Chromatography Tandem Mass Spectrometry
Jian LU,* Zhong-Ping WU,* Wen-Jun CHE,* Yan-Ping XIAN,** Xin-Dong GUO,** Jia-Xin LV,*** and He LI***
*Jiangsu Product Quality Testing and Inspection Institute, Nanjing, Jiangsu 210007, China
**Guangzhou Quality Supervision and Testing Institute, Guangzhou 510110, China
***School of Chemistry and Environment, South China Normal University, Guangzhou 510006, China
A new method was developed for the determination of eight earthy-musty compounds in drinking water by gas chromatography tandem mass spectrometry (GC-MS/MS) combined with dispersive liquid–liquid microextraction (DLLME). In this work, the type and volume of extraction solvent and dispersion agent, and the amount of NaCl were optimized; the linearity, detection limit, recovery and precision of method were investigated. The results indicated that the target analytes were in the range of 0.2 – 100 μg/L with correlation coefficient (r) ranging from 0.9991 to 0.9999, the limit of detection (LOD, S/N = 3) of the analytes ranged from 0.2 to 1.0 ng/L with the enrichment factor of 320. The mean recoveries for drinking water at three spiked concentrations levels of 0.6 – 32 ng/L were in the range of 91.3 to 103%, the precision ranged from 3.1 to 7.5% (n = 6), and the inter-day precision was from 6.1 to 11.1% (n = 5). Only one of 15 selected real samples tested positive for GSM, and the concentration was 3 ng/L. This method was confirmed to be simple, fast, efficient, and accurate for the determination of earthy-musty compounds in aqueous samples.