Analytical Sciences

Abstract − Analytical Sciences, 32(2), 241 (2016).

Visual Assay of Total Iron in Human Serum with Bathophenanthrolin Disulfonate-accommodated MCM-41
Misato SAKAMOTO, Keita HIZAWA, Manabu HOSAKA, and Masao SUGAWARA
Department of Chemistry, College of Humanities and Sciences, Nihon University, Sakurajyosui, Setagaya, Tokyo 156-8550, Japan
A simple visual method for determining the total iron in human serum is proposed based on color development in the nanospace of mesoporous silica MCM-41 and a chromogenic ligand bathophenathroline disulfonate (BPS). Observing the color intensity of a complex between iron(II) and BPS devloped on the MCM-41 material by the naked eye enabled us to quntify iron(II) with a detection limit of 0.5 μM. The BPS-loaded MCM-41 was successfully applied for quantifying the total iron in human serum.