Analytical Sciences

Abstract − Analytical Sciences, 28(3), 291 (2012).

Evaluation of Electrodeposited Gold Nanostructures for Applications in QCM Sensing
Kyohei TERAO,* Chihiro KAKITA,* Noriko NAGASE,* Nobumitsu MIYANISHI,** Takaaki SUZUKI,* Hidekuni TAKAO,* Fusao SHIMOKAWA,* and Fumikazu OOHIRA*
*Department of Intelligent Mechanical Systems Engineering, Kagawa University, 2217-20 Hayashi, Takamatsu 761-0396, Japan
**Department of Food Life Sciences, Toyo University, 1-1-1 Izumino, Gunma 374-0193, Japan
The electrodeposition of gold nanostructures increases the surface area of a biosensor, which brings an enhancement of the sensitivity by increasing the amount of analyte binding to the surface. To evaluate the relationship among the surface structure, the area and the analyte binding, we quantitatively analyzed them for quartz crystal microbalance (QCM) sensing by scanning electron microscopy and cyclic voltammetry measurements. The results indicate a several-times increase of analyte bindings, and also the limitation of the sensing performance.