Analytical Sciences

Abstract − Analytical Sciences, 25(3), 453 (2009).

Analytical Method for Perchlorate in Water by Liquid Chromatography-Mass Spectrometry Using an Ion Exchange Column
Masahiro KAMOSHITA, Koji KOSAKA, Mari ASAMI, and Yukiko MATSUOKA
Department of Water Supply Engineering, National Institute of Public Health, 2-3-6 Minami, Wako, Saitama 351-0197, Japan
A practical analytical method was developed for the routine analysis of perchlorate in environmental and drinking-water samples by liquid chromatography-electrospray ionization mass spectrometry (LC/ESI-MS) using an anion exchange column. By using 18O-enriched perchlorate as an internal standard, the limits of quantification of perchlorate determined by tenfold of the signal-to-noise ratio and tenfold of the standard deviation were 0.1 and 0.03 µg L-1, respectively. The perchlorate concentrations in the raw and finished water samples from seven water purification plants were determined by LC/ESI-MS. Perchlorate was detected in 12 out of 13 samples, and the perchlorate concentrations in the samples were from 0.1 to 36.1 µg L-1.