Analytical Sciences


Abstract − Analytical Sciences, 22(12), 1605 (2006).

Determination of Manganese in Urine and Whole Blood Samples by Electrothermal Atomic Absorption Spectrometry: Comparison of Chemical Modifiers
Frederico Garcia PINTO,* Ulisses Villela REY,* Eduardo Freitas FERNANDES,** Josianne Nicácio SILVEIRA,** Leiliane AMORIM,** and José Bento Borba da SILVA*
*Departamento de Química, Universidade Federal de Minas Gerais, Avenida Antônio Carlos 6627, 31270-901 Belo Horizonte, MG, Brazil
**Laboratório de Toxicologia Ocupacional, Faculdade de Farmácia, Universidade Federal de Minas Gerais, Avenida Antônio Carlos 6627, 31270-901 Belo Horizonte, MG, Brazil
In this work, methodologies to determine manganese (Mn) in urine and whole blood by electrothermal atomic absorption spectrometry were developed. The use of Ru, Rh, and Zr as permanent modifiers, Pd as a modifier in solution, and the condition without modifier were investigated for the direct determination of Mn in urine and whole blood samples. The best results for Mn in urine and in whole blood were obtained without modifier use. The analytical characteristic, such as accuracy, precision and limit of detection of the proposed methodology were adequate.