Analytical Sciences

Abstract − Analytical Sciences, 18(1), 19 (2002).

Enantiomer Separation by Capillary Electrochromatography Using Fritless Packed Columns
Department of Chemistry, Hamamatsu University School of Medicine, 1-20-1, Handayama, Hamamatsu 431-3192, Japan
This review summarizes recent developments in the field of enantiomer separation by capillary electrochromatography using fritless packed columns. Various enantiomers have been separated by employing fritless packed columns prepared in a fused silica capillary either by the immobilization of chiral packing materials by sintering or sol-gel technology or by in situ polymerization of a mixture containing chiral selectors. The details of the column preparation procedures and the attainable column performance are described.