Analytical Sciences

Abstract − Analytical Sciences, 17(12), 1389 (2001).

A Non-potentiometric Sensing Method for the Determination of Pentoxyverine with PQC Sensors Based on Ion-pair Complexes
Jinbin YUAN, Yong'an HU, Lihua NIE, and Shouzhou YAO 
Chemistry & Chemical Engineering College, Hunan University, Changsha, 410082, P. R. China
The construction and general performance characteristics of three piezoelectric quartz crystal sensors responsive to the pentoxyverine are described here. This kind of non-potentiometric sensing method is based on use of ion-pair complexes of the pentoxyverine cation with three counter anions, namely, tungstophosphate, tetraphenylborate and picrolonate. The complexes were embedded in a PVC matrix. Adsorption of the pentoxyverine ion on the complex caused a frequency decrease of the crystal. The frequency decrease was proportional to the amount of adsorbed analyte. The influencing factors were investigated in detail, and then optimized. The proposed sensors exhibit reasonable selectivity and a higher sensitivity than the potentiometric sensors. For a sensor modified with pentoxyverine-phosphotungstate, the calibration graph was linear over concentration of 1.0 x 10-7 - 5.0 x 10-5 M with a detection limit of 6 x 10-8 M at pH 5.4.