Analytical Sciences


Abstract − Analytical Sciences, 16(5), 463 (2000).

Adsorptive Behavior of Hemoglobin at a Platinum Electrode andIts Application to the Determination of Proteins
Chunhai FAN,* Xiaofang HU,* Genxi LI,* Ž€Û«ianqin ZHU,** and Dexu ZHU*
*Department of Biochemistry and National Key Laboratory of Pharmaceutical Biotechnology,Nanjing University, Nanjing 210093, P. R. China
**Department of Biology, Nanjing University, Nanjing 210093, P. R. China
The adsorptive behavior of hemoglobin at a platinum electrode is investigated by employing cyclic voltammetry. On the basis of the investigations, an electrochemical method for the determination of hemoglobin is developed. This method is shown to be simple and sensitive. The detection limit can be as low as 1.6 nmol/L. Since the working electrode does not need to be modified and the experimental procedure is very simple, this method might be useful for protein determination in the future.