Analytical Sciences


Abstract − Analytical Sciences, 14(5), 965 (1998).

Simultaneous Determination of Four Components in Composite Vitamin B Tablets Using a Square-Root Kalman Filter
Jinghe YANG* * , Rongjiang HAN**, Benyu SU***, Cunguo LIN*, Naixing WANG* and Jingtian HU*
*Department of Chemistry, Shandong University, Jinan 250100, P. R. China
**Department of Light Chemical Engineering, Shandong Institute of Light Industry, Jinan 250100, P. R. China
***Shandong Supervision & Inspection Institute for Product Quality, Jinan 250100, P. R. China
A square-root Kalman filter combined with spectrometry has been applied to determining the concentrations of vitamin B1, vitamin B2, vitamin B6 and nicotinamide in synthetic mixtures and in a commercial composite vitamin B tablet. A simultaneous assay of the components in synthetic mixtures containing the above mentioned four B-complex vitamins was successfully achieved with satisfactory recoveries of 97.0 - 103.3%. The components in a commercial composite vitamin B tablet were determined simultaneously, and the obtained results are in good agreement with the labeled con tents of the tablet. (Keywords: Square-root Kalman filter, spectrophotometry, simultaneous determination, composite vitamin B tablet)