Analytical Sciences

Abstract − Analytical Sciences, 14(1), 183 (1998).

Naked-Eye Detectable Chiral Recognition Using aChromogenicReceptor
Yuji KUBO * ,Naohisa HIROTA, Shi'nyaMAEDA and Sumio TOKITA
Department of AppliedChemistry, Faculty of Engineering, Saitama University, 255 Shimo-ohkubo, Urawa, Saitama 338, Japan
This article is concerned with our recent achievement in developingsynthetic chromogenic receptors for optical activeamines and amino acid derivatives. Pre-organized(S)-1,1'-bi-2-naphthyl- and bis(indophenol)-derived calix[4]crown1ashows naked-eye detectable chiral recognition between thoseenantiomers. The spectroscopic properties are reported, aswell as an estimation of the enantioselectivity using an HPLC equipped witha chiral packing column. (Keywords: Chromogenic receptor, indophenol, calixarene, chiralrecognition, chiral amine, amino acid)